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RI

RenovoRx, Inc. (RNXT)·Q1 2025 Earnings Summary

Executive Summary

  • First full quarter of commercial revenue: ~$0.20M from RenovoCath, exceeding internal expectations; management expects sequential quarterly growth for the foreseeable future .
  • EPS was approximately in line with consensus at -$0.08*, and revenue modestly beat consensus ($0.197M* vs. $0.183M*), aided by >10 non-trial institutions initiating POs and early reorder activity .
  • Cash of $14.6M at 3/31/25; management believes this will fully fund RenovoCath scale-up and continued progress toward TIGeR-PaC completion as device revenues ramp .
  • Key near-term catalyst: second interim analysis for TIGeR-PaC triggered (56/86 events as of May 2); DMC review expected in Q3 2025; full enrollment still targeted for 2025 .
  • Insider alignment: management and board purchased ~143K shares during the recent open window, signaling confidence in trajectory .

What Went Well and What Went Wrong

What Went Well

  • Strong commercial traction: “Q1 was our first full quarter of RenovoCath commercial sales, generating approximately $200,000 in revenue… we anticipate this positive trend to continue as we expect sequential quarterly growth” — CEO Shaun Bagai .
  • Demand signals broadened: >10 non‑TIGeR‑PaC medical institutions (including high‑volume NCI centers) initiated POs; early utilization led to repeat orders .
  • Operating preparedness and IP strengthening: Increased U.S. production to meet demand; new U.S. patent issued; portfolio now 19 issued patents globally (9 U.S.), plus 7 U.S. pending .

What Went Wrong

  • Loss widened YoY: Net loss was -$2.4M vs. -$1.1M in Q1’24, driven by higher operating loss and a $0.8M decrease in fair value of common warrant liability .
  • Opex up YoY as commercialization scales: R&D +$0.4M YoY on compensation, manufacturing/NRE, conferences; SG&A +$0.4M YoY on personnel and commercialization support .
  • International remains future optionality: No CE mark currently; company is prioritizing U.S. commercialization before pursuing OUS opportunities, which may defer ex-U.S. revenue ramp .

Financial Results

P&L vs prior periods and consensus

MetricQ3 2024Q4 2024Q1 2025Q1 2025 Consensus
Revenue ($USD Millions)0.043 0.197*0.183*
Diluted EPS ($)-0.08 -0.08*-0.08*
Net Loss ($USD Millions)-2.50 -2.42 -2.40

Notes: “—” indicates not disclosed in the referenced primary document for that period.
Values marked with * retrieved from S&P Global.

Operating expense detail (YoY)

Metric ($USD Millions)Q1 2024Q1 2025
R&D1.3 1.7
SG&A1.2 1.6
Net Loss1.1 2.4

Balance sheet snapshot

MetricDec 31, 2024Mar 31, 2025
Cash & Cash Equivalents ($USD Millions)7.154 14.582
Total Assets ($USD Millions)8.118 16.014
Total Liabilities ($USD Millions)3.640 2.857
Stockholders’ Equity ($USD Millions)4.478 13.157
Shares Outstanding (date)36.55M (3/25/25) 36.57M (5/9/25)

Commercial & clinical KPIs

KPIPrior Quarter (Q4 2024)Current (Q1 2025)Commentary
RenovoCath Revenue ($USD)~$43,000 ~$200,000 First full revenue quarter; exceeding internal expectations
Institutions initiating POs (non-trial)>10 (noted late Q4/early Q1) >10; reorder activity observed Early utilization leading to reorders
TIGeR-PaC Randomized Patients90 (as of 3/28/25) 91 (as of 5/2/25) Steady progress toward full enrollment in 2025
TIGeR-PaC Events (Deaths)50 (as of 3/28/25) 56 (as of 5/2/25) Triggered second interim analysis
Production capacityScaling up (Q4 plan) Increased U.S. production (Medical Murray) Aligning supply with demand
Insider purchases~143,000 shares open-market Alignment with shareholders

Guidance Changes

MetricPeriodPrevious GuidanceCurrent GuidanceChange
Revenue (qualitative)FY 2025“Q1 low six figures; sequential QoQ growth” (stated Apr/Apr 16) “Q1 delivered ~$200k; sequential growth expected for foreseeable future” Maintained/validated
Cash runway2025 opsCash + Feb raise to fund plan $14.6M at 3/31 expected to fully fund RenovoCath scale-up and TIGeR-PaC progress Maintained
TIGeR-PaC milestones202552nd event in 1H25; full enrollment 2025 Second interim triggered (56 events); DMC review in Q3 2025; full enrollment 2025 Timeline refined
Quantitative guidance (revenue/EPS/margins)None providedNone provided

No formal numerical guidance was issued; management continues to provide qualitative directional commentary.

Earnings Call Themes & Trends

TopicQ-2 (Q3 2024)Q-1 (Q4 2024)Current (Q1 2025)Trend
Commercialization tractionPreparing commercialization; near‑term revenue potential 2025 First POs; ~$43k revenue in Dec; >10 institutions initiated POs; reorders begin ~$200k revenue; >10 non‑trial institutions; reorders; targeting top 200 centers Improving
Production & supplyIncreased production plans Increased U.S. production with Medical Murray to meet demand Strengthening
Partnerships vs direct salesEvaluating direct vs partner channels Mgmt believes small focused team and/or partner can scale Actively evaluating strategic partners vs small internal sales team Ongoing evaluation
Clinical progress (TIGeR-PaC)Progress toward next interim; 52nd event expected late ‘24/early ‘25 90 randomized; 50 events (as of 3/28) 91 randomized; 56 events; DMC review in Q3 2025 Advancing
International expansionNo CE mark; focus on U.S. first; exploring OUS later Deferred
IP portfolio18 issued patents (Q4 narrative) New U.S. patent issued; 19 issued, 7 U.S. pending Expanding
Insider alignment~143K open‑market insider buys Positive signal

Management Commentary

  • “Q1 was our first full quarter of RenovoCath commercial sales, generating approximately $200,000 in revenue… we anticipate this positive trend to continue as we expect sequential quarterly growth for the foreseeable future.” — CEO Shaun Bagai .
  • “We expect the study’s data monitoring committee to review the data in Q3 and eagerly await their recommendations and feedback.” — CEO Shaun Bagai .
  • “As of March 31, 2025, the company had $14.6 million in cash and cash equivalents.” — VP Controller & PAO Ronald Kocak .
  • “The reception from the physician community has been overwhelmingly positive… [we observed] a 65% reduction in adverse events… and median overall survival… 10 months vs 16 months with our targeted approach.” — Founder & CMO Dr. Ramtin Agah (study interim context) .

Q&A Highlights

  • International expansion: No current CE mark; company prioritizes U.S. commercialization given favorable reimbursement, exploring OUS later this year or next .
  • Go-to-market model: Actively evaluating building a small internal sales force versus partnering with a strategic with existing interventional oncology distribution; both paths in progress to determine best financial outcome .

Estimates Context

  • Q1 2025 revenue modestly beat consensus: $0.197M* vs $0.183M*; EPS in line at -$0.08* with 3 estimates for both revenue and EPS*; target price consensus $5.44* (4 estimates).
    Values retrieved from S&P Global.

Key Takeaways for Investors

  • Early commercialization is working: sequential growth is underway, with ~$0.20M in Q1 device revenue and clear demand signals (top centers initiating POs, early reorders) .
  • Operating leverage potential: Management believes a small focused team or a strategic partner can drive meaningful penetration at ~200 top centers, potentially limiting opex growth as revenue scales .
  • Runway to catalysts: $14.6M cash should fund RenovoCath scale-up and TIGeR-PaC progress through a Q3 DMC review; full enrollment targeted for 2025—both key stock catalysts .
  • Clinical narrative building: interim data previously cited show survival and tolerability advantages; a positive DMC outcome would strengthen the device+therapy platform story .
  • Insider conviction: ~143K open-market purchases by management/board underscore confidence and can be a sentiment tailwind .
  • Watch for partner optionality: A distribution partnership could accelerate adoption and improve capital efficiency; near-term updates on commercial model could move shares .
  • Risk monitor: Losses widened YoY as the company invests in commercialization; revenue scale and DMC outcomes are central to de‑risking the path to cash flow positivity .

Footnotes:
Values marked with * retrieved from S&P Global.
Company reported “approximately $200 thousand” of Q1 2025 revenue .